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Home > Products >  Tebipenem Pivoxil

Tebipenem Pivoxil CAS NO.161715-24-8

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Keywords

  • Tetrahydropyran-4-Methanol
  • TBPM-PI
  • Orapenem

Quick Details

  • ProName: Tebipenem Pivoxil
  • CasNo: 161715-24-8
  • Molecular Formula: 161715-24-8
  • Application: oral carbapenem antibiotic.
  • ProductionCapacity: Metric Ton/Day
  • Purity: 99%
  • LimitNum: 0 Metric Ton

Superiority

mp  140-142℃
density  1.50
 
Safety Information
MSDS Information
 
 
(1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid pivaloyloxymethyl ester Usage And Synthesis
Chemical Properties White Solid
Usage Tebipenem Pivoxil is an oral carbapenem antibiotic. Tebipenem Pivoxil is absorbed and metabolized into Tebipenem, its active metabolite which showed excellent bactericidal activity against β-lactamase -nonproducing, ampicillin-resistant isolates.
Usage Tebipenem pivoxil(L-084) is a novel oral carbapenem antibiotic with an IC50 of 100 μg/ml for human CYP isoforms. In mouse, rat, dog and monkey, TBPM-PI were absorbed quickly, and the bioavailability was (71.4, 59.1, 34.8 and 44.9%, respectively. 

 

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